发布日期:2023-09-28
浏览次数:12次
研究方向:鱼类发育、细菌免疫逃逸
金沙8888js官方教授,博士生导师,浦江学者,东方学者。复旦大学博士,主要开展鱼类变态、肌间刺发育,鱼类和细菌协同进化,河鲀和河鲀毒素细菌等方面的研究。在Nature Genetics,Developmental Biology,Genomics等期刊发表130余篇学术论文,出版英文专著1部,曾获大北农科技奖创新奖、农业农村部神农中华农业科技一等奖,上海市科学技术进步奖等奖项。兼任中国鱼类学会副理事长、中国水产学会水产生物技术与遗传育种专业委员会委员、中国自然资源学会海洋资源专业委员会委员、Marine Biotechnology期刊编委。
01 代表性著作
[1] Zhang B, Shao C, Chen S, Bao B, 2022, Understanding asymmetrical malpigmentation in flatfishes and improvement measures for aquaculture. Review in Aquaculture, 00:1-12. DOI: 10.1111/raq.12652.
[2] Lei Gao, Yajuan Huang, Mingyan Sun, Baolong Bao, The role of autophagy on eye migration during the metamorphosis of Paralichthys olivaceus. Cells & Development 169 (2022) 203751.
[3] Xue He, Hexing Wu, Yaping Ye, Xiaolin Gong and Baolong Bao. Transcriptome analysis revealed gene expression feminization of testis after exogenous tetrodotoxin administration in puferfsh Takifugu favidus. BMC Genomics (2022) 23:553 https://doi.org/10.1186/s12864-022-08787-z.
[4] Lei Gao, Rachit Penglee, Yajuan Huang, Xinxin Yi, Xiaojie Wang,Liping Liu, Xiaoling Gong, Baolong Bao(鲍宝龙), 2021,CRISPR/Cas9-induced nos2b mutant zebrafish display behavioral abnormalities. Genes Brain Behav, 20(5):e12716.
[5] Rachit Penglee, Gao Lei, Baolong Bao, 2021(鲍宝龙). The role of nitric oxide and neuronal nitric oxide synthase in zebrafish (Danio rerio) shoaling. Aquaculture and Fisheries,6(6): 565-573.
[6] Yufeng Si, Hui Li, Xiaoling Gong *, Baolong Bao*, 2021. Isolation of prolactin gene and its differential expression during metamorphosis involving eye migration of Japanese flounder Paralichthys olivaceus.Gene, 780:145522. doi: 10.1016/j.gene.2021.145522.
[7] Bo Zhang, Kangkang Peng, Jinyuan Che, Na Zhao, Lei Jia, Dongkang Zhao, YaJuan Huang, YongGuan Liao, Xiaoxu He, Xiaoling Gong, Baolong Bao, 2021. Single-nucleotide polymorphisms responsible for pseudo-albinism and hypermelanosis in Japanese flounder (Paralichthys olivaceus) and reveal two genes related to malpigmentation. Fish Physiol Biochem (2021) 47:339–350.
[8] Bo Zhang, Lei Jia, Xiaoxu He, Chunxiu Chen, Hao Liu, Kefeng Liu, Na Zhao, Baolong Bao. 2020. Large scale SNP unearthing and genetic architecture analysis in sea-captured and cultured populations of Cynoglossus semilaevis. Genomics,112(5):3238-3246.
[9] Bo Zhang, Na Zhao, Kangkang Peng, Xiaoxu He, Chun Xiu Chen, Hao Liu, Kefeng Liu, Lei Jia, Baolong Bao,2020. A combination of genome-wide association study screening and SNaPshot for detecting sex-related SNPs and genes in Cynoglossus semilaevis. Comparative Biochemistry and physiology D-Genomics & & Proteomics, 35:100711.
[10] Kangkang Peng, Bo Zhang, Juan Xu, Na Zhao, Lei Jia, Jinyuan Che, Xiaoxu He, Kefeng Liu, XiaolingGong,BaolongBao,2020. Identification of SNPs related to hypermelanosis of the blind side by transcriptome profiling in the Japanese flounder (Paralichthys olivaceus). Aquaculture,519:734906.
[11] Jubin Xing, Zhonghe Ke, Liping Liu, Chenhong Li, Xiaoling Gong, Baolong Bao, 2019.Eye location, cranial asymmetry, and swimming behavior of different variants of Solea senegalensis. Aquaculture and Fisheries. https://doi.org/10.1016/j.aaf.2019.11.003.
[12] Bo Zhang, Na zhao, Lei Jia, Jinyuan Che , Xiaoxu He, Kefeng Liu, Baolong Bao,2020. Identification and application of piwi-interacting RNAs from seminal plasma exosomes in Cynoglossus semilaevis, 2020, BMC Genomics, 302 (2020). https://doi.org/10.1186/s12864-020-6660-7
02 近期主要科研项目
[1] 国家自然科学基金面上项目:比目鱼类体色左右不对称及体色异常产生的机理, 主持
[2] 国家自然科学基金面上项目:TTX合成相关基因在河鲀体内各种产TTX共生细菌间的水平转移规律,主持
[3] 国家自然科学基金面上项目:细胞分裂和细胞迁移对比目鱼类眼睛移动的作用,主持
[4] 国家自然科学基金面上项目:甲状腺激素调控比目鱼眼睛移动的细胞分裂信号途径,主持
[5] 国家自然科学基金面上项目:蓝光诱导近海硬骨鱼类黑色隐蔽伪装色形成的机理,主持
[6] 国家自然科学基金面上项目:真骨鱼类肌间刺进化又退化的发育基础,主持。
03 代表性专利
[1] 鲍宝龙、柯中和、邢巨斌、龚小玲、谢彩霞、徐冰、盖军伟.所有申请人姓名. 一种抑制比目鱼眼睛移动的方法.专利号:ZL201010179362.3(发明专利)
[2] 鲍宝龙、杨桂梅. 产河豚毒素的气单胞菌发酵培养和所产河豚毒素的检测方法.专利号:ZL201010179363.8(发明专利)
[3]鲍宝龙、卢瑛、马廷龙、李静、刘静、张莉君.降解河豚毒素的提取液及其制备方法.专利号:ZL201310135898.9(发明专利)
[4] 鲍宝龙、姚文杰、吕耀平、张莉君.一种抑制鱼鳞形成的方法. 专利号:ZL201310329623.9(发明专利)
04 专著和教材情况
[1]主编译著《水产基因组学技术》,中国化工出版社,2011年4月第1版
[2]参与专著《鱼类基因组学及基因组育种技术》(陈松林主编)编写,科学出版社,2017年第1版。
05 近期荣誉、获奖
[1] 2004年,《鱼类学》CAI课件,高等教育上海市级教学成果三等奖。
[2] 2004年,中国五大湖三角帆蚌优异种质评价与筛选,上海市科学技术进步三等奖。
[3] 2009年,鱼类学精品课程建设的探索与实践,上海市教学成果奖一等奖。
[4] 2017年,人工智能鱼为抓手探索多学科融合的教学设计与创新实践,2017年上海市高等教育教学成果一等奖。
[5] 2018年,牙鲆重要性状的遗传解析及基因组选择育种技术的建立与应用,2018年中国水产科学研究院大渔创新奖。
[6] 2021年鲆鳎鱼类重要性状遗传解析及分子育种技术创建与良种创制,农业农村部神农中华农业科技一等奖。
[7] 2021年,鲆鲽鱼类发育异常的机制解析和防控技术建立,大北农科技奖创新奖。
发布日期:2023-09-28
浏览次数:12次
研究方向:鱼类发育、细菌免疫逃逸
金沙8888js官方教授,博士生导师,浦江学者,东方学者。复旦大学博士,主要开展鱼类变态、肌间刺发育,鱼类和细菌协同进化,河鲀和河鲀毒素细菌等方面的研究。在Nature Genetics,Developmental Biology,Genomics等期刊发表130余篇学术论文,出版英文专著1部,曾获大北农科技奖创新奖、农业农村部神农中华农业科技一等奖,上海市科学技术进步奖等奖项。兼任中国鱼类学会副理事长、中国水产学会水产生物技术与遗传育种专业委员会委员、中国自然资源学会海洋资源专业委员会委员、Marine Biotechnology期刊编委。
01 代表性著作
[1] Zhang B, Shao C, Chen S, Bao B, 2022, Understanding asymmetrical malpigmentation in flatfishes and improvement measures for aquaculture. Review in Aquaculture, 00:1-12. DOI: 10.1111/raq.12652.
[2] Lei Gao, Yajuan Huang, Mingyan Sun, Baolong Bao, The role of autophagy on eye migration during the metamorphosis of Paralichthys olivaceus. Cells & Development 169 (2022) 203751.
[3] Xue He, Hexing Wu, Yaping Ye, Xiaolin Gong and Baolong Bao. Transcriptome analysis revealed gene expression feminization of testis after exogenous tetrodotoxin administration in puferfsh Takifugu favidus. BMC Genomics (2022) 23:553 https://doi.org/10.1186/s12864-022-08787-z.
[4] Lei Gao, Rachit Penglee, Yajuan Huang, Xinxin Yi, Xiaojie Wang,Liping Liu, Xiaoling Gong, Baolong Bao(鲍宝龙), 2021,CRISPR/Cas9-induced nos2b mutant zebrafish display behavioral abnormalities. Genes Brain Behav, 20(5):e12716.
[5] Rachit Penglee, Gao Lei, Baolong Bao, 2021(鲍宝龙). The role of nitric oxide and neuronal nitric oxide synthase in zebrafish (Danio rerio) shoaling. Aquaculture and Fisheries,6(6): 565-573.
[6] Yufeng Si, Hui Li, Xiaoling Gong *, Baolong Bao*, 2021. Isolation of prolactin gene and its differential expression during metamorphosis involving eye migration of Japanese flounder Paralichthys olivaceus.Gene, 780:145522. doi: 10.1016/j.gene.2021.145522.
[7] Bo Zhang, Kangkang Peng, Jinyuan Che, Na Zhao, Lei Jia, Dongkang Zhao, YaJuan Huang, YongGuan Liao, Xiaoxu He, Xiaoling Gong, Baolong Bao, 2021. Single-nucleotide polymorphisms responsible for pseudo-albinism and hypermelanosis in Japanese flounder (Paralichthys olivaceus) and reveal two genes related to malpigmentation. Fish Physiol Biochem (2021) 47:339–350.
[8] Bo Zhang, Lei Jia, Xiaoxu He, Chunxiu Chen, Hao Liu, Kefeng Liu, Na Zhao, Baolong Bao. 2020. Large scale SNP unearthing and genetic architecture analysis in sea-captured and cultured populations of Cynoglossus semilaevis. Genomics,112(5):3238-3246.
[9] Bo Zhang, Na Zhao, Kangkang Peng, Xiaoxu He, Chun Xiu Chen, Hao Liu, Kefeng Liu, Lei Jia, Baolong Bao,2020. A combination of genome-wide association study screening and SNaPshot for detecting sex-related SNPs and genes in Cynoglossus semilaevis. Comparative Biochemistry and physiology D-Genomics & & Proteomics, 35:100711.
[10] Kangkang Peng, Bo Zhang, Juan Xu, Na Zhao, Lei Jia, Jinyuan Che, Xiaoxu He, Kefeng Liu, XiaolingGong,BaolongBao,2020. Identification of SNPs related to hypermelanosis of the blind side by transcriptome profiling in the Japanese flounder (Paralichthys olivaceus). Aquaculture,519:734906.
[11] Jubin Xing, Zhonghe Ke, Liping Liu, Chenhong Li, Xiaoling Gong, Baolong Bao, 2019.Eye location, cranial asymmetry, and swimming behavior of different variants of Solea senegalensis. Aquaculture and Fisheries. https://doi.org/10.1016/j.aaf.2019.11.003.
[12] Bo Zhang, Na zhao, Lei Jia, Jinyuan Che , Xiaoxu He, Kefeng Liu, Baolong Bao,2020. Identification and application of piwi-interacting RNAs from seminal plasma exosomes in Cynoglossus semilaevis, 2020, BMC Genomics, 302 (2020). https://doi.org/10.1186/s12864-020-6660-7
02 近期主要科研项目
[1] 国家自然科学基金面上项目:比目鱼类体色左右不对称及体色异常产生的机理, 主持
[2] 国家自然科学基金面上项目:TTX合成相关基因在河鲀体内各种产TTX共生细菌间的水平转移规律,主持
[3] 国家自然科学基金面上项目:细胞分裂和细胞迁移对比目鱼类眼睛移动的作用,主持
[4] 国家自然科学基金面上项目:甲状腺激素调控比目鱼眼睛移动的细胞分裂信号途径,主持
[5] 国家自然科学基金面上项目:蓝光诱导近海硬骨鱼类黑色隐蔽伪装色形成的机理,主持
[6] 国家自然科学基金面上项目:真骨鱼类肌间刺进化又退化的发育基础,主持。
03 代表性专利
[1] 鲍宝龙、柯中和、邢巨斌、龚小玲、谢彩霞、徐冰、盖军伟.所有申请人姓名. 一种抑制比目鱼眼睛移动的方法.专利号:ZL201010179362.3(发明专利)
[2] 鲍宝龙、杨桂梅. 产河豚毒素的气单胞菌发酵培养和所产河豚毒素的检测方法.专利号:ZL201010179363.8(发明专利)
[3]鲍宝龙、卢瑛、马廷龙、李静、刘静、张莉君.降解河豚毒素的提取液及其制备方法.专利号:ZL201310135898.9(发明专利)
[4] 鲍宝龙、姚文杰、吕耀平、张莉君.一种抑制鱼鳞形成的方法. 专利号:ZL201310329623.9(发明专利)
04 专著和教材情况
[1]主编译著《水产基因组学技术》,中国化工出版社,2011年4月第1版
[2]参与专著《鱼类基因组学及基因组育种技术》(陈松林主编)编写,科学出版社,2017年第1版。
05 近期荣誉、获奖
[1] 2004年,《鱼类学》CAI课件,高等教育上海市级教学成果三等奖。
[2] 2004年,中国五大湖三角帆蚌优异种质评价与筛选,上海市科学技术进步三等奖。
[3] 2009年,鱼类学精品课程建设的探索与实践,上海市教学成果奖一等奖。
[4] 2017年,人工智能鱼为抓手探索多学科融合的教学设计与创新实践,2017年上海市高等教育教学成果一等奖。
[5] 2018年,牙鲆重要性状的遗传解析及基因组选择育种技术的建立与应用,2018年中国水产科学研究院大渔创新奖。
[6] 2021年鲆鳎鱼类重要性状遗传解析及分子育种技术创建与良种创制,农业农村部神农中华农业科技一等奖。
[7] 2021年,鲆鲽鱼类发育异常的机制解析和防控技术建立,大北农科技奖创新奖。